CAUTION: Investigational Device – Limited by United States law to investigational use. Endospan devices bear the CE marking of conformity.


Prospective, non-randomized, multi-center clinical investigation of the NEXUS™ Aortic Arch Stent Graft System (NEXUS) for the treatment of thoracic aortic lesions involving the aortic arch with a proximal landing zone, native or previously implanted surgical graft, in the ascending aorta and with a brachiocephalic trunk native landing zone


Aorta Arch Solutions

D'Onofrio, A. Vascular News 2020

"Augusto D’Onofrio, Giorgia Cibin, and Michele Antonello outline the features and benefits of the JOTEC E-vita OPEN NEO and the NEXUS Aortic Arch Stent Graft System for the treatment of aortic arch pathologies."

Bailout Implantation of a New Single

Branch Stent Graft for the Aortic Arch

Cibin, G. The Journal of Thoracic and Cardiovascular Surgery 2020.

"Endovascular stent grafting of the aortic arch is a new promising emerging technology that allows the exclusion of aortic arch aneurysms through a micro-invasive procedure."

Early Results of Arch Disease Treated with Nexus Arch Endograft

Lindsay, T. Journal of Vascular Surgery 2017.

"Our early experience with the Nexus arch graft has been successful in treating challenging arch aneurysmal disease without stroke or mortality in a high-risk population."

First Experience With the New NEXUS Stent Graft for the Arch

Mangialardi, N. Journal of Vascular Surgery 2015.

"We believe that this graft will play a large role in the treatment of arch pathologies."


"Novel modular design with minimal arch manipulation • Arch debranching is still a major procedure • Favorable early results with no mortality, spinal cord ischemia or strokes • Applicable to arch aneurysms and type A dissections with ascending aortic grafts in place that require arch and descending aortic coverage"

Early Canadian Experience with the NEXUS Arch Graft 

Lindsay, T. Linc Conference 2017.

"Effective minimally invasive option for aortic pathology involving the aortic arch • Approved Off-the-Shelf Solution (Feb. 2019) • Promising mid term results • Low procedural time results in procedural predictability"

Update on the NEXUS Off-The-Shelf Single Branch Device

Lachat, M. Veith Symposium 2019.

Case Studies
Bailout Implantation Of A New Single-Branched Stent Graft For The Aortic Arch

Due to an uneventful and minimally invasive procedure, the patient was able to be discharged 7 days post op. Six month follow up CT angiogram (Fig 2) shows stable position of NEXUS™ and total exclusion of the anastomotic pseudoaneurysm.

Symptomatic Aortic Arch Contained Rupture

Due to the minimally invasive nature of the procedure, the patient was able to leave her bed very quickly and was discharged within a few days, with her recovery time reduced from several weeks.

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